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Eating a fatty meal prior to or throughout the therapy can slow down the absorption process and make Sildenafil less effective.
Similar to any type of various other medication, Sildenafil requires particular care when you start taking various other medicines, specifically atazanavir, erythromycin, heart medications, cimetidine, indinavir, telithromycin, saquinavir, imatinib, fosamprenavir, delavirdine, bosentan, antifungals, conivaptan, nelfinavir, isoniazid, clarithromycin, rifampin or antidepressants.